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The efficacy of High Intensity Interval Training (HIIT) versus aerobic exercise in the early stage of Parkinson’s Disease: A Systematic Review
Journal article   Open access   Peer reviewed

The efficacy of High Intensity Interval Training (HIIT) versus aerobic exercise in the early stage of Parkinson’s Disease: A Systematic Review

Soufiane El Kichouhi El Hantari and Polykarpos Angelos Nomikos
F1000 research, Vol.14, 1273
18/11/2025

Abstract

Purpose Exercise is shown to be effective in Parkinson’s Disease (PD), but there is still controversy over which type of exercise is most effective. This study aimed to evaluate the efficacy of High-intensity interval training (HIIT) versus aerobic training in motor and non-motor symptoms in PD. Materials and Methods A literature search was performed since February 2024 to July 2025 in MEDLINE, EMBASE, Discovery @Bolton, PsycINFO, Google Scholar, PubMed, CINAHL, and SPORTDiscus. Data extracted by a single reviewer and cross checked by another. The risk of bias was assessed using the Revised Cochrane risk of bias tool, and quality of reporting was assessed using the Template for Intervention Description and Replication (TiDieR) checklist. Results The search yielded 9 studies involving a total of 263 people with PD in the early stages. The results from the risk of bias showed that 88.8% of studies were judged to be of moderate to high quality. The completeness of intervention reporting showed overall moderate (66.1%) quality of reporting. Conclusion HIIT showed improvement in physiological, cognitive, and overall quality of life (QoL) outcomes when compared to aerobic exercise. HIIT also showed significant improvement in cognitive function. PROSPERO Registration Number : CRD42023478541, 02 November 2023.
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