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Leveraging deep learning and explainable AI  for diagnosis of prostate cancer
Conference proceeding   Open access   Peer reviewed

Leveraging deep learning and explainable AI for diagnosis of prostate cancer

Ibrahim Kosoko, Sarika Jain, Anchal Garg and Pradeep Hewage
2025 12th International Conference on Reliability, Infocom Technologies and Optimization (Trends and Future Directions) (ICRITO)
12th International Conference on Reliability, Infocom technologies and Optimization (ICRITO'2025) (Noida NCR, India, 18/09/2025–19/09/2025)
27/11/2025

Abstract

XAI Explainable Artificial intelligence Artificial intelligence Deep learning Convolutional Neural Networks Gleason Biopsy Whole slide images Prostate Cancer
This research explores the use of explainable artificial intelligence techniques in diagnosis of prostate cancer. This study uses whole slide images for prostate cancer detection. The study uses various deep learning models such as CNN, ResNet50, VGG19, DenseNet, MobileNet, Xception for image classification. VGG19 outperformed all the other models based on the evaluation metrics. GRAD-CAM, an explainable AI technique was applied to VGG19 model to understand the outcome of the classification. The study's results are encouraging because they showed not only better accuracy but an interpretation of the result using XAI techniques. Following these disclosures, a methodical classification procedure was implemented, dividing the Gleason grades into their respective classes.
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